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T72321

AZ13705339 hemihydrate

TargetMol

- Open Babel Depiction N N HO CH 3 N N CH 3 S O O N H N H 3 C F N

DESCRIPTION

AZ13705339 hemihydrate is a hemihydrate form of AZ13705339, exhibiting high potency and selectivity as a PAK1 inhibitor, demonstrating IC50 values of 0.33 nM for PAK1 and 59 nM for pPAK1. It also shows strong binding affinities with Kd values of 0.28 nM for PAK1 and 0.32 nM for PAK2. This compound is utilized in cancer research.

DETAILS

  • Purity: 98%
  • Smiles: CCS(=O)(C1=C(N2CCN(C)CC2)C=CC(NC3=NC=C(F)C(N(C4=C(C)C=CC(CO)=C4)CC5=CC=CC=C5C#N)=N3)=C1)=O.CCS(=O)(C6=C(N7CCN(C)CC7)C=CC(NC8=NC=C(F)C(N(C9=C(C)C=CC(CO)=C9)CC%10=CC=CC=C%10C#N)=N8)=C6)=O.O
  • Category: Compound
  • Molecular Weight: 638.77
  • Molecular Formula: C33H36FN7O3S.1/2H2O

Lead Time: Please Inquire

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