PBK Antibody (Y74) Blocking Peptide

DETAILS

Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Gene Id: 55872
Category: Peptides; Blocking Peptides
Subtitle: Synthetic peptide
Gene Name: PBK
Other Names: Lymphokine-activated killer T-cell-originated protein kinase, Cancer/testis antigen 84, CT84, MAPKK-like protein kinase, Nori-3, PDZ-binding kinase, Spermatogenesis-related protein kinase, SPK, T-LAK cell-originated protein kinase, PBK, TOPK
Availability: 2 weeks
Bio Background: PBK is a serine/threonine kinase related to the dual specific mitogen-activated protein kinase kinase (MAPKK) family. Evidence suggests that mitotic phosphorylation is required for its catalytic activity. This mitotic kinase may be involved in the activation of lymphoid cells and support testicular functions, with a suggested role in the process of spermatogenesis.
Bio References: Nandi, A., et al., Blood Cells Mol. Dis. 32(1):240-245 (2004).Simons-Evelyn, M., et al., Blood Cells Mol. Dis. 27(5):825-829 (2001).Zhao, S., et al., Int. J. Biochem. Cell Biol. 33(6):631-636 (2001).Abe, Y., et al., J. Biol. Chem. 275(28):21525-21531 (2000).Gaudet, S., et al., Proc. Natl. Acad. Sci. U.S.A. 97(10):5167-5172 (2000).
Primary Accession: Q96KB5
Targetspecificity: The synthetic peptide sequence used to generate the antibody AP7164f was selected from the Y74 region of human PBK. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.