FOLR1 Antibody (N-term) Blocking Peptide

DETAILS

Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Gene Id: 2348
Category: Peptides; Blocking Peptides
Subtitle: Synthetic peptide
Gene Name: FOLR1
Other Names: Folate receptor alpha, FR-alpha, Adult folate-binding protein, FBP, Folate receptor 1, Folate receptor, adult, KB cells FBP, Ovarian tumor-associated antigen MOv18, FOLR1, FOLR
Availability: 2 weeks
Bio Background: The protein encoded by this gene is a member of the folatereceptor family. Members of this gene family bind folic acid andits reduced derivatives, and transport 5-methyltetrahydrofolateinto cells. This gene product is a secreted protein that eitheranchors to membranes via a glycosyl-phosphatidylinositol linkage orexists in a soluble form. Mutations in this gene have beenassociated with neurodegeneration due to cerebral folate transportdeficiency. Due to the presence of two promoters, multipletranscription start sites, and alternative splicing, multipletranscript variants encoding the same protein have been found forthis gene.
Bio References: Sivakumaran, S., et al. J. Steroid Biochem. Mol. Biol. 122(5):333-340(2010)Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)O'Byrne, M.R., et al. Birth Defects Res. Part A Clin. Mol. Teratol. 88(8):689-694(2010)Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) :Elwood, P.C., et al. Biochemistry 36(6):1467-1478(1997)
Primary Accession: P15328