T3S0737
Flavokawain A
TargetMol
DESCRIPTION
NSC-37445 has anti-tumor activity, such as inhibits growth of bladder tumor cells in a nude mice model , prevents the recurrence and progression of non-muscle-invasive urothelial cell carcinoma. NSC-37445 can significantly reduce the expression of CDK1-inhibitory kinases, Myt1 and Wee1, and cause cyclin B1 protein accumulation leading to CDK1 activation in T24 cells. 3. Flavokawain A (Flavokavain A) may exert anti-inflammatory responses by suppressing LPS-induced expression of pro-inflammatory mediators via blockage of NF-κB-AP-1-JNK/p38 MAPK signaling pathways in the murine macrophages.
DETAILS
- Cas: 3420-72-2
- Purity: 99.72%
- Smiles: COc1ccc(\C=C\C(=O)c2c(O)cc(OC)cc2OC)cc1
- Category: Compound
- Molecular Weight: 314.33
- Molecular Formula: C18H18O5
Lead Time: < 1 week
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