Cynomolgus PADI2 Protein, His Tag (MALS verified)

DESCRIPTION

Protein-arginine deiminase type-2 (PADI2) are calcium-dependent histone-modifying enzymes whose activity is dysregulated in inflammatory diseases and cancer. This enzyme which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The type II enzyme is the most widely expressed family member. Known substrates for this enzyme include myelin basic protein in the central nervous system and vimentin in skeletal muscle and macrophages.

DETAILS

Tag: N-10×His
Host: InsectCells
Size: 1mg
Buffer: PBS, pH7.4
Format: Liquid
Purity: 95%
Source: Cynomolgus PADI2, His Tag (PA2-C5545) is expressed from Baculovirus-Insect cells. It contains AA Met 1 - Pro 665 (Accession # A0A2K5TST4-1).
Storage: -70℃
Category: Enzymes
Molecule: PADI2
Accession: XP_005544699.1
Conjugate: Unconjugated
Stability: ● The product MUST be stored at -70°C or lower upon receipt; ● -70°C for 3 months under sterile conditions.
Exp Region: Met 1 - Pro 665
Swiss-prot: A0A2K5TST4-1
Package Size: 1mg*1
Characteristics: This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 77.6 kDa. The protein migrates as 75-85 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level: 1.0 EU per μg
Molecular Weight: 77.6 kDa
Shipping Condition: Dry ice
Species Reactivity: Cynomolgus
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