Human NKG2A&CD94 Protein, Mouse IgG2a Fc Tag (MALS verified)

DESCRIPTION

CD94 plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus. NKG2A/CD159a is a transmembrane protein belonging to the CD94/NKG2 family of C-type lectin-like receptors that inhibits innate immune system activation. CD94 pairs with the NKG2 molecule as a heterodimer. The CD94/NKG2 complex, on the surface of natural killer cells interacts with Human Leukocyte Antigen (HLA)-E on target cells.

DETAILS

Tag: C-mFc(mIgG2a)
Host: HEK293
Size: 1mg
Buffer: 50 mM Tris, 100 mM Glycine, 150 mM NaCl, pH7.5
Format: Powder
Purity: 95%
Source: Human NKG2A&CD94, Mouse IgG2a Fc Tag (NC4-H5253) is expressed from human 293 cells (HEK293). It contains AA Ala 113 - Leu 233 (NKG2A) & Asp 57 - Ile 179 (CD94) (Accession # P26715-1 (NKG2A) & Q13241-1 (CD94)).
Storage: -20℃
Category: Bio-Markers & CD Antigens
Molecule: NKG2A & CD94
Accession: NP_002250.1 (NKG2A) &
Conjugate: Unconjugated
Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Exp Region: Ala 113 - Leu 233 (NKG2A) & Asp 57 - Ile 179 (CD94)
Swiss-prot: P26715-1 (NKG2A) & Q13241-1 (CD94)
Package Size: 500ug*2
Characteristics: This protein carries a mouse IgG2a Fc tag at the C-terminus. The protein has a calculated MW of 55.5 kDa. The protein migrates as 65-80 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level: 0.1 EU per μg
Molecular Weight: 55.5 kDa
Shipping Condition: RT
Species Reactivity: Human
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