ILA-C5249-100ug ILA-C5249-1mg
Cynomolgus IL-17A / CTLA-8 Protein, His Tag (MALS verified)
ACROBiosystems
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DESCRIPTION
Interleukin-17A (IL17A) is also known as cytotoxic T-lymphocyte-associated antigen 8 (CTLA8),which is a proinflammatory cytokine produced by activated T cells. IL17A can regulate the activities of NF-kappaB and mitogen-activated protein kinases. Also,IL17A can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO).Furthermore,IL17A has been found both in glycosylated and nonglycosylated forms. High levels of IL-17 are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.
DETAILS
- Tag: N-10×His
- Host: HEK293
- Size: 1mg
- Buffer: PBS, pH7.4
- Format: Powder
- Purity: 90%
- Source: Cynomolgus IL-17A, His Tag (ILA-C5249) is expressed from human 293 cells (HEK293). It contains AA Gly 24 - Ala 155 (Accession # XP_005552816.1).
- Storage: -20℃
- Category: Cytokines&Growth Factors
- Molecule: IL-17A
- Conjugate: Unconjugated
- Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
- Exp Region: Gly 24 - Ala 155
- Swiss-prot: G7P4U9-1
- Package Size: 250ug*4
- Characteristics: This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 17.0 kDa. The protein migrates as 18-19 kDa,24-25 kDa and 28-30 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Endotoxin Level: 1.0 EU per μg
- Molecular Weight: 17.0 kDa
- Shipping Condition: RT
- Species Reactivity: Cynomolgus
- Extra Shippinghandling Fee: Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/A48-Shipping-and-Payments.html