Biotinylated Human MIF Protein, His,Avitag™

DESCRIPTION

Macrophage migration inhibitory factor(MIF) is also known as Glycosylation-inhibiting factor(GIF), L-dopachrome isomerase, L-dopachrome tautomerase, Phenylpyruvate tautomerase. Interacts with CXCR2 extracellular domain, CD74 extracellular domain, COPS5 and BNIPL. The expression of MIF at sites of inflammation suggests a role as mediator in regulating the function of macrophages in host defense. Counteracts the anti-inflammatory activity of glucocorticoids. Has phenylpyruvate tautomerase and dopachrome tautomerase activity (in vitro), but the physiological substrate is not known. It is not clear whether the tautomerase activity has any physiological relevance, and whether it is important for cytokine activity.

DETAILS

Tag: C-10×His & C-Avi
Host: HEK293
Size: 200ug
Buffer: 25 mM MES, 500 mM NaCl, pH6.5
Format: Powder
Purity: 90%
Source: Biotinylated Human MIF, His,Avitag (MIF-H82E7) is expressed from human 293 cells (HEK293). It contains AA Pro 2 - Ala 115 (Accession # P14174-1).
Storage: -20℃
Category: MABSol® Biotin Labeled Proteins
Molecule: MIF
Accession: NP_002406.1
Conjugate: Biotin-labeled
Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Exp Region: Pro 2 - Ala 115
Swiss-prot: P14174-1
Package Size: 100ug*2
Characteristics: This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 16.0 kDa. The protein migrates as 20 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level: 1.0 EU per μg
Molecular Weight: 16.0 kDa
Shipping Condition: RT
Species Reactivity: Human
Extra Shippinghandling Fee: Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/A48-Shipping-and-Payments.html