DESCRIPTION

• Tag: C-10×His & C-Avi
• Host: HEK293
• Size: 25ug
• Buffer: 50 mM Sodium Citrate, 150 mM NaCl, pH5.5
• Format: Powder
• Purity: 85%
• Storage: -20℃
• Category: MABSol® Biotin Labeled Proteins
• Molecule: BLAME
• Accession: NP_064510.1
• Conjugate: Biotin-labeled
• Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
• Background: BLAME (B-lymphocyte activator macrophage expressed) is also known as SLAM family member 8(SLAMF8), CD353. BLAME is a cell surface receptor that is expressed upon activation of macrophages (MΦs) by IFN-γ or bacteria, is a negative regulator of ROS in response to Gram+ and Gram- bacteria. May play a role in B-lineage commitment and/or modulation of signaling through the B-cell receptor. SLAMF8 is a costimulatory molecule that affects the activation of macrophages in inflammation and in immunosuppression and inflammation response to glioma cells could aid immunotherapy for glioma.
• Exp Region: Ala 23 - Asp 233
• Swiss-prot: Q9P0V8-1
• Characteristics: This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 27.1 kDa. The protein migrates as 30-35 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
• Endotoxin Level: 1.0 EU per μg
• Molecular Weight: 27.1 kDa
• Shipping Condition: RT
• Species Reactivity: Human
• Extra Shippinghandling Fee: Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/A48-Shipping-and-Payments.html