ARPC1A Antibody (C-term) Blocking Peptide

DETAILS

Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Gene Id: 10552
Category: Peptides; Blocking Peptides
Subtitle: Synthetic peptide
Gene Name: ARPC1A
Other Names: Actin-related protein 2/3 complex subunit 1A, SOP2-like protein, ARPC1A, SOP2L
Availability: 2 weeks
Bio Background: ARPC1A is one of seven subunits of the human Arp2/3 protein complex. This subunit is a member of the SOP2 family of proteins and is most similar to the protein ARPC1B. The similarity between these two proteins suggests that they both may function as p41 subunit of the human Arp2/3 complex that has been implicated in the control of actin polymerization in cells. It is possible that the p41 subunit is involved in assembling and maintaining the structure of the Arp2/3 complex. Multiple versions of the p41 subunit may adapt the functions of the complex to different cell types or developmental stages.
Bio References: Laurila,E., Genes Chromosomes Cancer 48 (4), 330-339 (2009)Machesky,L.M., Biochem. J. 328 (PT 1), 105-112 (1997)
Primary Accession: Q92747
Targetspecificity: The synthetic peptide sequence used to generate the antibody AP6519b was selected from the C-term region of human ARPC1A. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.