RAC2 Blocking Peptide (C-term)

DETAILS

Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Gene Id: 5880
Category: Peptides; Blocking Peptides
Subtitle: Synthetic peptide
Gene Name: RAC2
Other Names: Ras-related C3 botulinum toxin substrate 2, GX, Small G protein, p21-Rac2, RAC2
Availability: 2 weeks
Bio Background: Plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses, such as secretory processes, phagocytose of apoptotic cells and epithelial cell polarization. Augments the production of reactive oxygen species (ROS) by NADPH oxidase.
Bio References: Didsbury J.,et al.J. Biol. Chem. 264:16378-16382(1989). Puhl H.L. III,et al.Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases. Collins J.E.,et al.Genome Biol. 5:R84.1-R84.11(2004). Kalnine N.,et al.Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases. Dunham I.,et al.Nature 402:489-495(1999).
Primary Accession: P15153
Targetspecificity: The synthetic peptide sequence is selected from aa 178-188 of HUMAN RAC2