BP21363b
RAC2 Blocking Peptide (C-term)
Abcepta
DETAILS
- Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
- Gene Id: 5880
- Category: Peptides; Blocking Peptides
- Subtitle: Synthetic peptide
- Gene Name: RAC2
- Other Names: Ras-related C3 botulinum toxin substrate 2, GX, Small G protein, p21-Rac2, RAC2
- Availability: 2 weeks
- Bio Background: Plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses, such as secretory processes, phagocytose of apoptotic cells and epithelial cell polarization. Augments the production of reactive oxygen species (ROS) by NADPH oxidase.
- Bio References: Didsbury J.,et al.J. Biol. Chem. 264:16378-16382(1989). Puhl H.L. III,et al.Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases. Collins J.E.,et al.Genome Biol. 5:R84.1-R84.11(2004). Kalnine N.,et al.Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases. Dunham I.,et al.Nature 402:489-495(1999).
- Primary Accession: P15153
- Targetspecificity: The synthetic peptide sequence is selected from aa 178-188 of HUMAN RAC2