Alexa Fluor™ 647-Labeled Human HLA-A*11:01&B2M&KRAS (VVVGAGGVGK) Complex ProteinStar Staining (Monomer)

DESCRIPTION

The Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) oncogene plays a critical role in the initiation and maintenance of pancreatic tumors and its signaling network represents a major target for therapeutic intervention. The Alex Fluor 647 labeled Human HLA-A*1101 KRAS (VVVGAGGVGK) complex protein is a complex of HLA-A*1101 of the MHC Class I, B2M, and VVVGAGGVGK peptide of the KRAS.

DETAILS

Tag: C-10×His
Host: HEK293
Size: 200ug
Buffer: PBS, pH7.4
Format: Powder
Purity: 90%
Source: Alexa Fluor 647-Labeled Human HLA-A*11:01&B2M&KRAS (VVVGAGGVGK) Complex Protein (HLS-HA2H8) is expressed from human 293 cells (HEK293). It contains AA Gly 25 - Thr 305 (HLA-A*11:01) & Ile 21 - Met 119 (B2M) & VVVGAGGVGK peptide (Accession # Q5S3G3-1 (HLA-A*11:01) & P61769 (B2M) & VVVGAGGVGK).
Storage: -20℃, aviod light
Category: Fluorescent labeled protein
Molecule: HLA-A*1101 & B2M & KRAS (VVVGAGGVGK)
Conjugate: AF647 Labeled
Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Exp Region: Gly 25 - Thr 305 (HLA-A*11:01) & Ile 21 - Met 119 (B2M) & VVVGAGGVGK peptide
Swiss-prot: Q5S3G3-1 & P61769 & VVVGAGGVGK
Package Size: 200ug*1
Characteristics: Alexa Fluor 647-Labeled Human HLA-A*11:01&B2M&KRAS (VVVGAGGVGK) Complex Protein is produced by co-expression of HLA and B2M loaded with KRAS peptide. This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 49.4 kDa and 11.7 kDa. The protein migrates as 57-75 kDa and 12 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level: 1.0 EU per μg
Molecular Weight: 49.4 kDa and 11.7 kDa
Shipping Condition: RT
Species Reactivity: Human
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