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HY-15584A

Taltobulin (trifluoroacetate)

MedChem Express

- Open Babel Depiction H 3 C CH 3 CH 3 H 3 C H 3 C CH 3 OH H 3 C N NH O N H O H 3 C H 3 C H 3 C O

DESCRIPTION

Taltobulin trifluoroacetate (HTI-286 trifluoroacetate), a synthetic analogue of the tripeptide hemiasterlin, is a potent antimicrotubule agent that circumvents P-glycoprotein-mediated resistance in vitro and in vivo. Taltobulin trifluoroacetate inhibits the polymerization of purified tubulin, disrupts microtubule organization in cells, and induces mitotic arrest, as well as apoptosis[1].

DETAILS

  • Purity: >98%
  • Smiles: CC(C)(C)[C@H](NC([C@H](C(C)(C1=CC=CC=C1)C)NC)=O)C(N([C@@H](C(C)C)/C=C(C(O)=O)\C)C)=O.O=C(O)C(F)(F)F
  • Lead Time: 1-2 days
  • Cas Number: 228266-41-9
  • Molecular Weight: 587.67
  • Molecular Formula: C29H44F3N3O6

Lead Time: < 1 week

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