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MU1-H5252-100ug MU1-H5252-1mg

Human Mucin-1 / MUC-1 Protein, Fc Tag

ACROBiosystems

DESCRIPTION

Membrane mucins have several functions in epithelial cells including cytoprotection, extravasation during metastases, maintenance of luminal structure, and signal transduction. MUC17, contains an extended, repetitive extracellular glycosylation domain and a carboxyl terminus with two EGF-like domains, a SEA module domain, a transmembrane domain, and a cytoplasmic domain with potential serine and tyrosine phosphorylation sites. Interacts via its C-terminus with PDZK1 and this interaction appears important for proper localization. Probably plays a role in maintaining homeostasis on mucosal surfaces.

DETAILS

  • Tag: C-Fc
  • Host: HEK293
  • Size: 100ug
  • Buffer: 50 mM Tris, 100 mM Glycine, pH7.5
  • Format: Powder
  • Purity: 95%
  • Source: Human Mucin-1, Fc Tag (MU1-H5252) is expressed from human 293 cells (HEK293). It contains AA Ser 33 - Gly 167 (Accession # AAI20976).
  • Storage: -20℃
  • Category: Bio-Markers & CD Antigens
  • Molecule: Mucin-1
  • Accession: AAI20976
  • Conjugate: Unconjugated
  • Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
  • Exp Region: Ser 33 - Gly 167
  • Swiss-prot: P15941
  • Package Size: 100ug*1
  • Characteristics: This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 40.8 kDa. The protein migrates as 50-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
  • Endotoxin Level: 1.0 EU per μg
  • Molecular Weight: 40.8 kDa
  • Shipping Condition: RT
  • Species Reactivity: Human
  • Extra Shippinghandling Fee: Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/A48-Shipping-and-Payments.html