MU1-H5252-100ug MU1-H5252-1mg
Human Mucin-1 / MUC-1 Protein, Fc Tag
ACROBiosystems
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DESCRIPTION
Membrane mucins have several functions in epithelial cells including cytoprotection, extravasation during metastases, maintenance of luminal structure, and signal transduction. MUC17, contains an extended, repetitive extracellular glycosylation domain and a carboxyl terminus with two EGF-like domains, a SEA module domain, a transmembrane domain, and a cytoplasmic domain with potential serine and tyrosine phosphorylation sites. Interacts via its C-terminus with PDZK1 and this interaction appears important for proper localization. Probably plays a role in maintaining homeostasis on mucosal surfaces.
DETAILS
- Tag: C-Fc
- Host: HEK293
- Size: 100ug
- Buffer: 50 mM Tris, 100 mM Glycine, pH7.5
- Format: Powder
- Purity: 95%
- Source: Human Mucin-1, Fc Tag (MU1-H5252) is expressed from human 293 cells (HEK293). It contains AA Ser 33 - Gly 167 (Accession # AAI20976).
- Storage: -20℃
- Category: Bio-Markers & CD Antigens
- Molecule: Mucin-1
- Accession: AAI20976
- Conjugate: Unconjugated
- Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
- Exp Region: Ser 33 - Gly 167
- Swiss-prot: P15941
- Package Size: 100ug*1
- Characteristics: This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 40.8 kDa. The protein migrates as 50-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Endotoxin Level: 1.0 EU per μg
- Molecular Weight: 40.8 kDa
- Shipping Condition: RT
- Species Reactivity: Human
- Extra Shippinghandling Fee: Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/A48-Shipping-and-Payments.html