Rat Integrin alpha 1 beta 1 (ITGA1&ITGB1) Heterodimer Protein, His Tag&Tag Free

DESCRIPTION

Integrin alpha-1/beta-1 is a receptor for laminin and collagen. The Integrin alpha-1/beta-1 and Integrin alpha-2/beta-1 integrins provide critical support for vascular endothelial growth factor signaling, endothelial cell migration, and tumor angiogenesis. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. Involved in anchorage-dependent, negative regulation of EGF-stimulated cell growth.

DETAILS

Tag: C-10×His | Native
Host: HEK293
Size: 1mg
Buffer: 50 mM Tris,150 mM NaCl,pH7.5
Format: Powder
Purity: 95%
Source: Rat ITGA1&ITGB1 Heterodimer Protein, His Tag&Tag Free (IT1-R52W7) is expressed from human 293 cells (HEK293). It contains AA Phe 29 - Pro 1142 (ITGA1) & Gln 21 - Asp 729 (ITGB1) (Accession # P18614-1 (ITGA1) & P49134-1 (ITGB1)).
Storage: -20℃
Category: Bio-Markers & CD Antigens
Molecule: Integrin alpha 1 beta 1
Conjugate: Unconjugated
Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Exp Region: Phe 29 - Pro 1142 (ITGA1) & Gln 21 - Asp 729 (ITGB1)
Swiss-prot: P18614-1 (ITGA1) & P49134-1 (ITGB1)
Package Size: 200ug*5
Characteristics: Rat ITGA1&ITGB1 Heterodimer Protein, His Tag&Tag Free, produced by co-expression of ITGA1 and ITGB1, has a calculated MW of 130.0 kDa (ITGA1) and 83.7 kDa (ITGB1). Subunit ITGA1 is fused with an acidic tail at the C-terminus and followed by a polyhistidine tag and subunit ITGB1 contains no tag but a basic tail at the C-terminus.
Endotoxin Level: 1.0 EU per μg
Molecular Weight: 130 kDa (ITGA1) & 83.7 kDa (ITGB1)
Shipping Condition: RT
Species Reactivity: Rat
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