MAGEA9 Antibody (Center) Blocking Peptide

DETAILS

Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Gene Id: 4108;728269
Category: Peptides; Blocking Peptides
Subtitle: Synthetic peptide
Gene Name: MAGEA9
Other Names: Melanoma-associated antigen 9, Cancer/testis antigen 19, CT19, MAGE-9 antigen, MAGEA9, MAGE9, MAGEA9A
Availability: 2 weeks
Bio Background: MAGEA9 is a member of the MAGEA gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 80% sequence identity between each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are expressed at a high level in a number of tumors of various histologic types, and are silent in normal tissues with the exception of testis and placenta. The MAGEA genes are clustered on chromosome Xq28. They may be implicated in some hereditary disorders, such as dyskeratosis congenita.
Bio References: Rogner, U.C., et al., Genomics 29(3):725-731 (1995).De Plaen, E., et al., Immunogenetics 40(5):360-369 (1994).
Other Accession: NP_005356
Primary Accession: P43362
Targetspecificity: The synthetic peptide sequence used to generate the antibody AP6170a was selected from the Center region of human MAGEA9 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.