HCoV-NL63 S1 protein, His Tag

DESCRIPTION

It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

DETAILS

Tag: C-10×His
Host: HEK293
Size: 100ug
Buffer: PBS, pH7.4
Format: Powder
Purity: 90%
Source: HCoV-NL63 S1 protein, His Tag (SIN-V52H3) is expressed from human 293 cells (HEK293). It contains AA Cys 19 - Val 717 (Accession # Q6Q1S2-1).
Storage: -20℃
Category: Viral Proteins
Molecule: Spike S1
Conjugate: Unconjugated
Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Exp Region: Cys 19 - Val 717
Swiss-prot: Q6Q1S2-1
Package Size: 100ug*1
Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 79.5 kDa. The protein migrates as 120-140 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level: 1.0 EU per μg
Molecular Weight: 79.5 kDa
Shipping Condition: RT
Species Reactivity: HCoV-NL63
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