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CTF-H82E6-25ug CTF-H82E6-200ug

Biotinylated Human CTGF / CCN2 Protein, His,Avitag™ (recommended for biopanning)

ACROBiosystems

DESCRIPTION

Biotinylated Human CTGF Protein, His,Avitag (CTF-H82E6) is expressed from human 293 cells (HEK293). It contains AA Gln 27 - Ala 349 (Accession # Q5M8T4-1).

DETAILS

  • Tag: C-10×His & C-Avi
  • Host: HEK293
  • Size: 25ug
  • Buffer: Tris with Potassium glutamate and Arginine, pH7.0
  • Format: Powder
  • Purity: 90%
  • Storage: -20℃
  • Category: MABSol® Biotin Labeled Proteins
  • Molecule: CTGF
  • Accession: NP_001892.1
  • Conjugate: Biotin-labeled
  • Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
  • Background: Connective Tissue Growth Factor (CTGF), also known as CCN2, is a member of the CCN (CCN1-6) family of modular matricellular proteins. Like other CCN proteins, mature human CTGF consists of IGF-binding protein domain, a vWF-C domain, a TSP-1 domain, and a cysteine knot heparin-binding domain. CTGF promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis. Analysis of CCN2 function in vivo has focused primarily on its key role as a mediator of excess ECM synthesis in multiple fibrotic diseases.
  • Exp Region: Gln 27 - Ala 349
  • Swiss-prot: Q5M8T4-1
  • Characteristics: This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 39.2 kDa. The protein migrates as 40-42 kDa and 43-45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
  • Endotoxin Level: 1.0 EU per μg
  • Molecular Weight: 39.2 kDa
  • Shipping Condition: RT
  • Species Reactivity: Human
  • Extra Shippinghandling Fee: Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/A48-Shipping-and-Payments.html