Mouse IL-17A / CTLA-8 Protein, His Tag (MALS verified)

DESCRIPTION

Interleukin-17A (IL17A) is also known as cytotoxic T-lymphocyte-associated antigen 8 (CTLA8),which is a proinflammatory cytokine produced by activated T cells. IL17A can regulate the activities of NF-kappaB and mitogen-activated protein kinases. Also,IL17A can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO).Furthermore,IL17A has been found both in glycosylated and nonglycosylated forms. High levels of IL-17 are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.

DETAILS

Tag: N-6×His
Host: HEK293
Size: 100ug
Buffer: PBS, pH7.4
Format: Powder
Purity: 90%
Source: Mouse IL-17A, His Tag (CT8-M5240) is expressed from human 293 cells (HEK293). It contains AA Ala 26 - Ala 158 (Accession # Q62386-1).
Storage: -20℃
Category: Cytokines&Growth Factors
Molecule: IL-17A
Accession: NP_034682.1
Conjugate: Unconjugated
Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Exp Region: Ala 26 - Ala 158
Swiss-prot: Q62386-1
Package Size: 100ug*1
Characteristics: This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 15.8 kDa. The protein migrates as 17-19 kDa and 21-24 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level: 1.0 EU per μg
Molecular Weight: 15.8 kDa
Shipping Condition: RT
Species Reactivity: Mouse
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