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SPD-C82H6-25ug SPD-C82H6-200ug

Biotinylated SARS-CoV-2 Spike NTD Protein, His,Avitag™ (BA.4 & BA.5/Omicron) (MALS verified)

ACROBiosystems

DESCRIPTION

Biotinylated SARS-CoV-2 Spike NTD, His,Avitag (BA.4 & BA.5/Omicron) (SPD-C82H6) is expressed from human 293 cells (HEK293). It contains AA Ser 13 - Leu 303 (Accession # QHD43416.1 (T19I, LPP24-26del, A27S, HV69-70del, G142D, V213G)). The spike mutations are identified on the SARS-CoV-2 Omicron variant (Pango lineage: BA.4 and BA.5).

DETAILS

  • Tag: C-10×His & C-Avi
  • Host: HEK293
  • Size: 200ug
  • Buffer: PBS, pH7.4
  • Format: Powder
  • Purity: 95%
  • Storage: -20℃
  • Category: MABSol® Biotin Labeled Proteins
  • Molecule: Spike NTD
  • Accession: QHD43416.1 (T19I, LPP24-26del, A27S, HV69-70del, G142D, V213G)
  • Conjugate: Biotin-labeled
  • Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
  • Background: It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
  • Exp Region: Ser 13 - Leu 303
  • Characteristics: This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 34.4 kDa. The protein migrates as 55-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
  • Endotoxin Level: 1.0 EU per μg
  • Molecular Weight: 34.4 kDa
  • Shipping Condition: RT
  • Species Reactivity: SARS-CoV-2
  • Extra Shippinghandling Fee: Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/A48-Shipping-and-Payments.html