PBX1 Antibody (C-term) Blocking Peptide

DETAILS

Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Gene Id: 5087
Category: Peptides; Blocking Peptides
Subtitle: Synthetic peptide
Gene Name: PBX1
Other Names: Pre-B-cell leukemia transcription factor 1, Homeobox protein PBX1, Homeobox protein PRL, PBX1, PRL
Availability: 2 weeks
Bio Background: PBX1 binds the sequence 5'-ATCAATCAA-3'. It acts as a transcriptional activator of PF4 in complex with MEIS1, and is converted into a potent transcriptional activator by the (1;19) translocation. It may have a role in steroidogenesis and, subsequently, sexual development and differentiation.
Bio References: Duesing,K., BMC Med. Genet. 9, 14 (2008)Chung,E.Y., Immunity 27 (6), 952-964 (2007)Qiu,Y., Am. J. Pathol. 170 (1), 152-159 (2007)
Primary Accession: P40424
Targetspecificity: The synthetic peptide sequence used to generate the antibody AP7285b was selected from the C-term region of human PBX1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.