Polyclonal Antibody to Raf1 (Ab-259)

DESCRIPTION

Involved in the transduction of mitogenic signals from the cell membrane to the nucleus. Part of the Ras-dependent signaling pathway from receptors to the nucleus. Protects cells from apoptosis mediated by STK3.

DETAILS

Gene: RAF1
App Id: WB,IHC
Antigen: Raf1 (Ab-259)
Gene Id: 5894
Isotype: Rabbit IgG
Format Id: Purified
Uniprot Id: P04049
Host Animal: Rabbit
Clonality Id: Polyclonal
Reactivity Id: Human,Mouse,Rat
Product Content: Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Alternative Name: C-RAF|| C-Raf|| CRAF
Application Note: Predicted MW: 73kd, Western blotting: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
Storage Condition: Store the antibody at 4°C, stable for 6 months. For ong-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Immunogen Information: Peptide sequence around aa.257~261 (S-T-S-T-P) derived from Human RAF.