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ILG-R5283-100ug ILG-R5283-1mg

Rat IL-2 R beta&IL-2 R gamma Heterodimer Protein, His Tag&Twin-Strep Tag (MALS verified)

ACROBiosystems

DETAILS

  • Tag: C-10×His | C-Twin-Strep
  • Host: HEK293
  • Size: 100ug
  • Buffer: PBS, pH7.4
  • Format: Powder
  • Purity: 95%
  • Storage: -20℃
  • Category: Bio-Markers & CD Antigens
  • Molecule: IL-2 R beta & IL-2 R gamma
  • Accession: NP_037327.1 | NP_543165.1
  • Conjugate: Unconjugated
  • Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
  • Background: Both Interleukin-2 receptor subunit beta and Interleukin-2 receptor subunit gamma are receptor for interleukin-2. Common subunit for the receptors for a variety of interleukins. Interacts with SHB upon interleukin stimulation. Probably in association with IL15RA, involved in the stimulation of neutrophil phagocytosis by IL15. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. IL2R exists in 3 different forms: a high affinity dimer, an intermediate affinity monomer (beta subunit), and a low affinity monomer (alpha subunit). The high and intermediate affinity forms also associate with a gamma subunit.
  • Exp Region: Ala 27 - Glu 239 (IL-2RB) & Ser 25 - Ala 262 (IL-2RG)
  • Swiss-prot: P26896-1 (IL-2RB) & Q68FU6-1 (IL-2RG)
  • Characteristics: Rat IL-2RB&IL-2RG Heterodimer Protein, His Tag&Twin-Strep Tag is produced by co-expression of IL-2RB and IL-2RG, has a calculated MW of 30.2 kDa (IL-2RB) and 34.7 kDa (IL-2RG). Subunit IL-2RB is fused with a polyhistidine tag at the C-terminus and subunit IL-2RG is fused with Twin-Strep tag at the C-terminus. The reducing (R) protein migrates as 40-50 kDa and 55-65 kDa respectively due to glycosylation.
  • Endotoxin Level: 1.0 EU per μg
  • Molecular Weight: 30.2 kDa | 34.7 kDa
  • Shipping Condition: RT
  • Species Reactivity: Rat
  • Extra Shippinghandling Fee: Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/A48-Shipping-and-Payments.html

DESCRIPTION

Rat IL-2RB&IL-2RG Heterodimer Protein, His Tag&Twin-Strep Tag (ILG-R5283) is expressed from human 293 cells (HEK293). It contains AA Ala 27 - Glu 239 (IL-2RB) & Ser 25 - Ala 262 (IL-2RG) (Accession # P26896-1 (IL-2RB) & Q68FU6-1 (IL-2RG)).