CALB2/CR Antibody (C-term) Blocking peptide

DETAILS

Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Gene Id: 794
Category: Peptides; Blocking Peptides
Subtitle: Synthetic peptide
Gene Name: CALB2
Other Names: Calretinin, CR, 29 kDa calbindin, CALB2, CAB29
Availability: 2 weeks
Bio Background: This gene encodes an intracellular calcium-binding proteinbelonging to the troponin C superfamily. Members of this proteinfamily have six EF-hand domains which bind calcium. This proteinplays a role in diverse cellular functions, including messagetargeting and intracellular calcium buffering. It also functions asa modulator of neuronal excitability, and is a diagnostic markerfor some human diseases, including Hirschsprung disease and somecancers. Alternative splicing results in multiple transcriptvariants.
Bio References: Toth, K., et al. Brain 133(9):2763-2777(2010)Iio, K., et al. Biochem. Biophys. Res. Commun. 393(4):565-570(2010)Raiko, I., et al. BMC Cancer 10, 242 (2010) :Melotti, A., et al. BMC Cancer 10, 54 (2010) :Schwaller, B., et al. Eur. J. Biochem. 230(2):424-430(1995)
Primary Accession: P22676
Targetspecificity: The synthetic peptide sequence used to generate the antibody AP14086b was selected from the C-term region of CALB2/CR. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.