T61872
Trk-IN-10
TargetMol
DESCRIPTION
Trk-IN-10 (Compound 14j) is a highly effective inhibitor of TRK, with an IC50 of 0.86 nM against TrkA and 6.92 nM against TrkA G595R. As an RTK, Trk is a crucial drug target in solid tumors. Trk-IN-10 (IC50 = 350 nM against ALK) demonstrates superior selectivity in inhibiting Trk, potentially reducing toxicity [1].
DETAILS
- Cas: 2700265-61-6
- Purity: 98%
- Smiles: C[C@H]1N2C=3C(=CN4C(N3)=C(C=N4)C(=O)NC[C@H](C)OC=5C(C2)=CC=C(F)C5)OC1
- Category: Compound
- Molecular Weight: 397.4
- Molecular Formula: C20H20FN5O3
Lead Time: 5 + weeks
Sign in to view pricing