BP18464c
PARP1 Antibody (Center S782) Blocking Peptide
Abcepta
DETAILS
- Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
- Gene Id: 142
- Category: Peptides; Blocking Peptides
- Subtitle: Synthetic peptide
- Gene Name: PARP1
- Other Names: Poly [ADP-ribose] polymerase 1, PARP-1, ADP-ribosyltransferase diphtheria toxin-like 1, ARTD1, NAD(+) ADP-ribosyltransferase 1, ADPRT 1, Poly[ADP-ribose] synthase 1, PARP1, ADPRT, PPOL
- Availability: 2 weeks
- Bio Background: This gene encodes a chromatin-associated enzyme,poly(ADP-ribosyl)transferase, which modifies various nuclearproteins by poly(ADP-ribosyl)ation. The modification is dependenton DNA and is involved in the regulation of various importantcellular processes such as differentiation, proliferation, andtumor transformation and also in the regulation of the molecularevents involved in the recovery of cell from DNA damage. Inaddition, this enzyme may be the site of mutation in Fanconianemia, and may participate in the pathophysiology of type Idiabetes.
- Bio References: Majewski, P.M., et al. J. Biol. Chem. 285(45):34828-34838(2010)Kim, M., et al. Cancer Sci. 101(11):2436-2442(2010)Dong, Y., et al. Cancer Res. 70(20):8088-8096(2010)Krishnakumar, R., et al. Mol. Cell 39(5):736-749(2010)Lee, K.A., et al. Rheumatol. Int. (2010) In press :
- Primary Accession: P09874