Lactoylglutathione Lyase(CPTC-GLO1-1), CF640R conjugate, 0.1mg/mL

DESCRIPTION

GLO1 is an enzyme involved in the detoxification of methylgyoxal, a byproduct of glycolysis. GLO1 expression has been demonstrated by several studies to be upregulated in various human malignant tumors, including metastatic melanoma and lung carcinoma, and thus is a target for pharmaceutical development. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

DETAILS

Host: Mouse
Unigene: 268849
Shipping: Room temperature
Conjugate: CF640R
Swissprot: Q04760
Shelf-life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Genusspecies: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Antibody-type: Primary
Concentration: 0.1 mg/mL
Entrez-gene-id: 2739
Product Origin: Animal
Storage Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular-weight: 24-26 kDa
Positive-control: A431, HepG2, MOLT and Raji cell lysates. Ovarian carcinoma or prostate carcinoma.
Tumor-expression: Lung cancer|Melanoma
Attributesynonyms: Aldoketomutase; epididymis secretory protein Li 74; Glo1; Glx I; glyoxalase 1 complex; glyoxalase 1 regulatory; glyoxalase 1 structural; glyoxalase domain containing 1; Glyoxalase I; glyoxylase 1; Ketone-aldehyde mutase; lactoyl glutathione lyase; Lactoylglutathione lyase; Methylglyoxalase; S-D-lactoylglutathione methylglyoxal lyase
Human-gene-symbol: GLO1
Regulatory-status: For research use only (RUO)
Species-reactivity: Human
Storage-conditions: Store at 2 to 8°C|Protect fluorescent conjugates from light
Antibody-reactivity: Lactoylglutathione Lyase
Monoclonalpolyclonal: Monoclonal
Product Applications: IHC, FFPE (verified)|WB (verified)
Ab-target-localization: Cytoplasmic
Z-antibody-applications: IHC, FFPE (verified)|WB (verified)
Verified-ab-applications: IHC (FFPE) (verified)|WB (verified)
Validated-in-protein-array: Monospecific
Classified or Regulated Chemicals: 0.05% sodium azide (CAS 26628-22-8)
Clone Secondaries for Monoclonal Only: CPTC-GLO1-1
Immunogen Secondaries for Anti-tag Only: Recombinant human full-length GLO1 protein
Isotype Secondaries for Monoclonal Only: IgG1, kappa