Human FGF19 Protein, Fc Tag

DESCRIPTION

Fibroblast growth factor (FGF)19 is the first members of a new subfamily of FGFs and could act as hormones. During fetal life, FGF15/19 is involved in organogenesis, affecting the development of the ear, eye, heart, and brain. FGFs–FGFRs are involved in regulation of many biological processes such as embryonic development, cell proliferation, differentiation, and tissue repair. The dysregulation of FGF–FGFR was observed in different types of diseases, disorders, and cancers. Notably, aberrant expression of FGF19/FGFR4 contributes to Hepatocellular Carcinoma progression.

DETAILS

Tag: C-Fc
Host: HEK293
Size: 100ug
Buffer: 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
Format: Powder
Purity: 90%
Source: Human FGF19, Fc Tag (FG9-H5253) is expressed from human 293 cells (HEK293). It contains AA Leu 25 - Lys 216 (Accession # O95750-1).
Storage: -20℃
Category: Cytokines&Growth Factors
Molecule: FGF19
Accession: NP_005108.1
Conjugate: Unconjugated
Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Exp Region: Leu 25 - Lys 216
Swiss-prot: O95750-1
Package Size: 100ug*1
Characteristics: This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 47.9 kDa. The protein migrates as 50-55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level: 1.0 EU per μg
Molecular Weight: 47.9 kDa
Shipping Condition: RT
Species Reactivity: Human
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