Surface Coating: Azide PEG Amount: 20 mg Description Our single-layer poly (lactic-co-glycolic acid) (PLGA) nanoparticles form nanostructures with a hydrophobic core encapsulated inside a hydrophilic shell. PLGA surface contains COOH groups that can be used for EDC/NHS based bioconjugation. Optional surface modifications include methoxy PEG (improves in vivo blood half-life) and PEG-Azide (can be used to covalently attach biomolecules by click chemistry). Features Made with FDA approved biocompatible and biodegradable PLGA polymer. Conjugation-ready for covalent attachment of biomolecules. High degree of monodispersity. (Optional) Incorporation of Methoxy-PEG minimizes non-specific protein adsorption. This increase nanoparticle in-vivo blood half-life. (Optional) Incorporation of Azide-PEG allows conjugation of proteins and small molecules by click chemistry. Applications In vitro and in vivo delivery of proteins and small molecules. Product is supplied as lyophilized powder.