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ILA-H5255-100ug ILA-H5255-1mg

Human IL-3 R alpha / CD123 Protein, Llama IgG2b Fc Tag, low endotoxin

ACROBiosystems

DETAILS

  • Tag: C-LlamaFc(LlamaIgG2b)
  • Host: HEK293
  • Size: 100ug
  • Buffer: Tris with Glycine, Arginine and NaCl, pH7.5
  • Format: Powder
  • Purity: 90%
  • Storage: -20℃
  • Category: Bio-Markers & CD Antigens
  • Molecule: IL-3 R alpha
  • Accession: NP_002174.1
  • Conjugate: Unconjugated
  • Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
  • Background: Interleukin 3 receptor alpha (low affinity) (IL3RA), also known as CD123 (Cluster of Differentiation 123) is a 70-kD glycoprotein member of the hematopoietin receptor superfamily. This protein associates with a beta subunit common to the receptors for IL-5 and granulocyte-macrophage colony-stimulating factor (GM-CSF) to form a high-affinity receptor for IL-3. The interleukin-3 receptor α chain (CD123) has been identified as a potential immunotherapeutic target because it is overexpressed in AML compared with normal hematopoietic stem cells.
  • Exp Region: Thr 19 - Arg 305
  • Swiss-prot: P26951-1
  • Characteristics: This protein carries a llama IgG2b Fc tag at the C-terminus. The protein has a calculated MW of 60.9 kDa. The protein migrates as 45 kDa, 55 kDa and 80 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
  • Endotoxin Level: 0.01 EU per μg
  • Molecular Weight: 60.9 kDa
  • Shipping Condition: RT
  • Species Reactivity: Human
  • Extra Shippinghandling Fee: Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/A48-Shipping-and-Payments.html

DESCRIPTION

Human IL-3 R alpha Protein, Llama IgG2b Fc Tag (ILA-H5255) is expressed from human 293 cells (HEK293). It contains AA Thr 19 - Arg 305  (Accession # P26951-1).