Human BDNF / Abrineurin Protein, premium grade

DESCRIPTION

Brain-derived neurotrophic factor (BDNF) along with nerve growth factor (NGF), neurotrophin-3 (NT-3), and neurotrophin-4/5 (NT-4/5) are members of the neurotrophin family of trophic factors. The neurotrophins play essential roles in the development, survival, and function of a wide range of neurons in both the peripheral and central nervous systems. The neurotrophins interact with two cell surface receptors, the low affinity P75 receptor and the Trk family of high affinity tyrosine kinase receptors. NGF preferentially binds TrkA, BDNF and NT4/5 bind TrkB, and NT-3 binds TrkC (and TrkA to a lesser extent).

DETAILS

Tag: Native
Host: HEK293
Size: 1mg
Buffer: PBS, pH7.4
Format: Powder
Purity: 95%
Source: Human BDNF, premium grade (BDF-H5219) is expressed from human 293 cells (HEK293). It contains AA His 129 - Arg 247 (Accession # P23560-1).
Storage: -20℃
Category: Cytokines&Growth Factors
Molecule: BDNF
Conjugate: Unconjugated
Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Exp Region: His 129 - Arg 247
Swiss-prot: P23560-1
Package Size: 500ug*2
Characteristics: This protein carries no "tag". The protein has a calculated MW of 13.5 kDa. The protein migrates as 15-17 kDa and 19 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level: 0.01 EU per μg
Molecular Weight: 13.5 kDa
Shipping Condition: RT
Species Reactivity: Human
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