Biotinylated Human CD45 / PTPRC Protein, His,Avitag™

DESCRIPTION

CD45 is a receptor protein tyrosine phosphatase, also known as Ly-5 or leukocyte common antigen. CD45 mainly involves in the initiation of T cell receptor signaling by controlling the activation of the Src family protein-tyrosine kinases Lck and Fyn. CD45 deficiency causes in T- and B-lymphocyte dysfunction in the form of severe combined immune deficiency. It also takes a significant role in autoimmune diseases and cancer as well as in infectious diseases including fungal infections.

DETAILS

Tag: C-Fc & C-Avi
Host: HEK293
Size: 200ug
Buffer: PBS, pH7.4
Format: Powder
Purity: 90%
Source: Biotinylated Human CD45 / PTPRC Protein, His,Avitag (CD5-H82E8) is expressed from human 293 cells (HEK293). It contains AA Gln 26 - Lys 482 (Accession # P08575-8).
Storage: -20℃
Category: MABSol® Biotin Labeled Proteins
Molecule: CD45
Conjugate: Biotin-labeled
Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Exp Region: Gln 26 - Lys 482
Swiss-prot: P08575-8
Package Size: 200ug*1
Characteristics: This protein carries a human IgG1 Fc tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 54.9 kDa. The protein migrates as 120-150 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level: 1.0 EU per μg
Molecular Weight: 54.9 kDa
Shipping Condition: RT
Species Reactivity: Human
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