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MIA-H5256-100ug MIA-H5256-1mg

Human MICA (24-202) Protein, Llama IgG2b Fc Tag, low endotoxin (MALS verified)

ACROBiosystems

DESCRIPTION

Human MICA (24-202) Protein, Llama IgG2b Fc Tag (MIA-H5256) is expressed from human 293 cells (HEK293). It contains AA Glu 24 - Arg 202 (Accession # Q29983-1).

DETAILS

  • Tag: C-LlamaFc(LlamaIgG2b)
  • Host: HEK293
  • Size: 1mg
  • Buffer: 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
  • Format: Powder
  • Purity: 90%
  • Storage: -20℃
  • Category: Other Recombinant Proteins
  • Molecule: MICA
  • Conjugate: Unconjugated
  • Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
  • Background: MHC class I polypeptide-related sequence A (MICA) belongs to the MHC class I family and MIC subfamily. MICA contains one Ig-like C1-type (immunoglobulin-like) domain. Unlike classical MHC class I molecules, MICA does not form a heterodimer with beta-2-microglobulin. MICA acts as a stress-induced self-antigen that is recognized by gamma delta T-cells. MICA is ligand for the KLRK1/NKG2D receptor. MICA bind to KLRK1 leads to cell lysis.
  • Exp Region: Glu 24 - Arg 202
  • Swiss-prot: Q29983-1
  • Characteristics: This protein carries a llama IgG2b Fc tag at the C-terminus. The protein has a calculated MW of 48.8 kDa. The protein migrates as 60-65 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
  • Endotoxin Level: 0.01 EU per μg
  • Molecular Weight: 48.8 kDa
  • Shipping Condition: RT
  • Species Reactivity: Human
  • Extra Shippinghandling Fee: Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/A48-Shipping-and-Payments.html