ACSL4 Antibody (N-term) Blocking Peptide

DETAILS

Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Gene Id: 2182
Category: Peptides; Blocking Peptides
Subtitle: Synthetic peptide
Gene Name: ACSL4
Other Names: Long-chain-fatty-acid--CoA ligase 4, Long-chain acyl-CoA synthetase 4, LACS 4, ACSL4, ACS4, FACL4, LACS4
Availability: 2 weeks
Bio Background: The protein encoded by this gene is an isozyme of thelong-chain fatty-acid-coenzyme A ligase family. Although differingin substrate specificity, subcellular localization, and tissuedistribution, all isozymes of this family convert free long-chainfatty acids into fatty acyl-CoA esters, and thereby play a key rolein lipid biosynthesis and fatty acid degradation. This isozymepreferentially utilizes arachidonate as substrate. The absence ofthis enzyme may contribute to the mental retardation or Alportsyndrome. Alternative splicing of this gene generates 2 transcriptvariants.
Bio References: Bosker, F.J., et al. Mol. Psychiatry (2010) In press :Zhang, Y., et al. Hum. Mol. Genet. 18(20):3894-3905(2009)Zeman, M., et al. Tohoku J. Exp. Med. 217(4):287-293(2009)An, C., et al. Neurosci. Lett. 441(2):197-200(2008)Hu, C., et al. Cancer Biol. Ther. 7(1):131-134(2008)
Primary Accession: O60488