SARS-CoV-2 Spike RBD Protein, His Tag (BA.2.11/Omicron) (MALS verified)

DESCRIPTION

It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

DETAILS

Tag: C-10×His
Host: HEK293
Size: 100ug
Buffer: PBS, pH7.4
Format: Powder
Purity: 95%
Source: SARS-CoV-2 Spike RBD, His Tag (BA.2.11/Omicron) (SPD-C522s) is expressed from human 293 cells (HEK293). It contains AA Arg 319 - Lys 537 (Accession # QHD43416.1 (G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H)). The spike mutations are identified on the SARS-CoV-2 Omicron variant (Pango lineage: BA.2.11; GISAID clade: GRA).
Storage: -20℃
Category: Viral Proteins
Molecule: Spike RBD
Accession: QHD43416.1 (G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H)
Conjugate: Unconjugated
Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Exp Region: Arg 319 - Lys 537
Package Size: 100ug*1
Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 26.7 kDa. The protein migrates as 33-38 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level: 1.0 EU per μg
Molecular Weight: 26.7 kDa
Shipping Condition: RT
Species Reactivity: SARS-CoV-2
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