BP7239a
Scientist.com Supplier
STK11 (LKB1) Antibody (N-term I29) Blocking peptide
Abcepta
DETAILS
- Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
- Gene Id: 6794
- Category: Peptides; Blocking Peptides
- Subtitle: Synthetic peptide
- Gene Name: STK11
- Other Names: Serine/threonine-protein kinase STK11, Liver kinase B1, LKB1, hLKB1, Renal carcinoma antigen NY-REN-19, STK11, LKB1, PJS
- Availability: 2 weeks
- Bio Background: STK11, is a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in STK11 have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms.
- Bio References: Mart, et al., J. Biotechnol. 115(1):23-34 (2005).Shaw, R.J., et al., Proc. Natl. Acad. Sci. U.S.A. 101(10):3329-3335 (2004).Suzuki, A., et al., Biochem. Biophys. Res. Commun. 324(3):986-992 (2004).Hearle, N., et al., Genes Chromosomes Cancer 41(2):163-169 (2004).Corradetti, M.N., et al., Genes Dev. 18(13):1533-1538 (2004).
- Primary Accession: Q15831
- Targetspecificity: The synthetic peptide sequence used to generate the antibody AP7239a was selected from the N-term region of human STK11 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.