PDGFRB Antibody Blocking Peptide

DETAILS

Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Gene Id: 5159
Category: Peptides; Blocking Peptides
Subtitle: Synthetic peptide
Gene Name: PDGFRB
Other Names: Platelet-derived growth factor receptor beta, PDGF-R-beta, PDGFR-beta, Beta platelet-derived growth factor receptor, Beta-type platelet-derived growth factor receptor, CD140 antigen-like family member B, Platelet-derived growth factor receptor 1, PDGFR-1, CD140b, PDGFRB, PDGFR, PDGFR1
Availability: 2 weeks
Bio Background: PDGFRB is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides.
Bio References: Wu, H., et al., J. Biol. Chem. 278(42):40425-40428 (2003).Whiteman, E.L., et al., Endocrinology 144(9):3811-3820 (2003).Uren, A., et al., Oncogene 22(15):2334-2342 (2003).Steer, E.J., et al., Acta Haematol. 107(2):113-122 (2002).Kawagishi, J., et al., Genomics 30(2):224-232 (1995).
Primary Accession: P09619
Targetspecificity: The synthetic peptide sequence used to generate the antibody AP7667d was selected from the region of human PDGFRB. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.