T35985
Scientist.com Supplier
CAY10487
TargetMol
DESCRIPTION
The early stage of atherosclerosis is characterized by the aggregation of foam cells, so called a fatty streak, in the inner arterial wall. CAY10487 inhibits formation of fatty streak lesions of the thoracic aorta in high cholesterol-fed rabbits without affecting plasma lipid profiles or significantly inhibiting ACAT-1 or ACAT-2 activity. The percent area occupied by the atherosclerotic lesion in rabbits supplemented with 0.05% CAY10487 in the diet was 16.1% compared to 53.5% in control rabbits. CAY10487 also exhibits antioxidant activity, inhibiting copper-mediated oxidation of low-density lipoprotein by about 75% at a concentration of 2 μM.
DETAILS
- Cas: 778624-05-8
- Purity: 98%
- Smiles: C(=C/C(N[C@H](C(OC)=O)C)=O)\C1=CC(O)=C(O)C=C1
- Category: Compound
- Molecular Weight: 265.26
- Molecular Formula: C13H15NO5
Lead Time: Please Inquire
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