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HLV-H52E5-25ug HLV-H52E5-200ug

Unconjugated Human HLA-A*11:01&B2M&KRASG12V (VVVGAVGVGK) Complex Protein (Monomer, MALS verified)

ACROBiosystems

DESCRIPTION

Unconjugated Human HLA-A*11:01&B2M&KRASG12V (VVVGAVGVGK) Complex Protein (HLV-H52E5) is expressed from human 293 cells (HEK293). It contains AA Gly 25 - Thr 305 (HLA-A*11:01) & Ile 21 - Met 119 (B2M) & VVVGAVGVGK peptide (Accession # Q5S3G3-1 (HLA-A*11:01) & P61769 (B2M) & VVVGAVGVGK).

DETAILS

  • Tag: C-10×His & C-Avi
  • Host: HEK293
  • Size: 200ug
  • Buffer: PBS, pH7.4
  • Format: Powder
  • Purity: 90%
  • Storage: -20℃
  • Category: Other Recombinant Proteins
  • Molecule: HLA-A*1101 & B2M & KRASG12V (VVVGAVGVGK)
  • Conjugate: Unconjugated
  • Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
  • Background: The Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) oncogene plays a critical role in the initiation and maintenance of pancreatic tumors and its signaling network represents a major target for therapeutic intervention. The Human HLA-A*1101 KRASG12V (VVVGAVGVGK) complex protein is a complex of HLA-A*1101 of the MHC Class I, B2M, and VVVGAVGVGK peptide of the KRASG12V.
  • Exp Region: Gly 25 - Thr 305 (HLA-A*11:01) & Ile 21 - Met 119 (B2M) & VVVGAVGVGK peptide
  • Swiss-prot: Q5S3G3-1 & P61769 & VVVGAVGVGK
  • Characteristics: Unconjugated Human HLA-A*11:01&B2M&KRASG12V (VVVGAVGVGK) Complex Protein is produced by co-expression of HLA and B2M loaded with KRASG12V peptide. This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™), and it is not biotinylated. The protein has a calculated MW of 36.0 kDa and 11.7 kDa. The protein migrates as 40-42 kDa and 11 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
  • Endotoxin Level: 1.0 EU per μg
  • Molecular Weight: 36.0 kDa and 11.7 kDa
  • Shipping Condition: RT
  • Species Reactivity: Human
  • Extra Shippinghandling Fee: Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/A48-Shipping-and-Payments.html