BP12388a
ZNF146 Antibody (N-term) Blocking peptide
Abcepta
DETAILS
- Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
- Gene Id: 7705
- Category: Peptides; Blocking Peptides
- Subtitle: Synthetic peptide
- Gene Name: ZNF146
- Other Names: Zinc finger protein OZF, Only zinc finger protein, Zinc finger protein 146, ZNF146, OZF
- Availability: 2 weeks
- Bio Background: The ZNF146 protein is a 33 kDa Kruppel protein, composed solely of 10 zinc finger motifs. ZNF146 overexpression in tumours may alter the balance between hRap1 and other telomeric proteins; therefore ZNF146 function may be linked to telomere regulation. ZNF146 is strongly overexpressed in many pancreas and colorectal cancers. Increased gene copy numbers are detected in 3 of 12 tumor cell lines and 2 of 12 primary pancreatic carcinomas. ZNF146 is overexpresseed in 80% of colorectal cancers.
- Bio References: Antoine, K., et al. J. Cell. Biochem. 95(4):763-768(2005)Antoine, K., et al. Mol. Cell. Biochem. 271 (1-2), 215-223 (2005) :Grimwood, J., et al. Nature 428(6982):529-535(2004)Ferbus, D., et al. J. Pathol. 200(2):177-182(2003)Pibouin, L., et al. Cytogenet. Cell Genet. 92 (1-2), 80-84 (2001) :
- Primary Accession: Q15072