CDL-H5255-100ug CDL-H5255-1mg
Human CD27 Ligand / CD70 Protein, Llama IgG2b Fc Tag, low endotoxin
ACROBiosystems
Image
![](https://www.acrobiosystems.com/static/main/products/images/sds/CDL-H5255.jpg)
Image
![](https://www.acrobiosystems.com/static/main/products/images/elisa/CDL-H5255-E1.jpg)
Image
![](https://www.acrobiosystems.com/static/main/products/images/elisa/CDL-H5255-E2.jpg)
Image
![](https://www.acrobiosystems.com/static/main/products/images/elisa/CDL-H5255-E1.jpg)
DESCRIPTION
Cluster of Differentiation 70 (CD70) is also known as CD27 ligand (CD27L / CD27LG), TNFSF7, TNFSF7G, is a type II transmembrane glycoprotein belonging to the TNF superfamily (TNFSF) and is a surface antigen found on activated T-and B-lymphocytes and mature dendritic cells. Binding of CD70 to its receptor CD27 induces in priming, effector functions, differentiation and memory formation of T-cells, and thus is invloved in the biological processes including T-cell activation, the proliferation of costimulated T-cells, as well as the generation of cytolytic T-cells. CD70 on T cells provides costimulatory signals that are required for T cell proliferation, clonal expansion and the promotion of effector T cell formation. CD70 on mouse B cell has been shown to inhibit terminal differentiation of activated B cells into plasma cells and enhances commitment to memory B cell responses. CD70 induces proliferation and IFNγ production, on NK cells.
DETAILS
- Tag: N-LlamaFc(LlamaIgG2b)
- Host: HEK293
- Size: 100ug
- Buffer: 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
- Format: Powder
- Purity: 95%
- Source: Human CD27 Ligand, Llama IgG2b Fc Tag (CDL-H5255) is expressed from human 293 cells (HEK293). It contains AA Ser 52 - Pro 193 (Accession # NP_001243.1).
- Storage: -20℃
- Category: Immune Checkpoint Proteins
- Molecule: CD27 Ligand
- Accession: NP_001243.1
- Conjugate: Unconjugated
- Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
- Exp Region: Ser 52 - Pro 193
- Swiss-prot: P32970-1
- Package Size: 100ug*1
- Characteristics: This protein carries a llama IgG2b Fc tag at the N-terminus. The protein has a calculated MW of 75.5 kDa. The protein migrates as 140-160 kDa under non-reducing (NR) condition (SDS-PAGE) due to glycosylation.
- Endotoxin Level: 0.01 EU per μg
- Molecular Weight: 75.5 kDa
- Shipping Condition: RT
- Species Reactivity: Human
- Extra Shippinghandling Fee: Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/A48-Shipping-and-Payments.html