HTR3A Antibody (N-term) Blocking peptide

DETAILS

Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Gene Id: 3359
Category: Peptides; Blocking Peptides
Subtitle: Synthetic peptide
Gene Name: HTR3A
Other Names: 5-hydroxytryptamine receptor 3A, 5-HT3-A, 5-HT3A, 5-hydroxytryptamine receptor 3, 5-HT-3, 5-HT3R, Serotonin receptor 3A, Serotonin-gated ion channel receptor, HTR3A, 5HT3R, HTR3
Availability: 2 weeks
Bio Background: The product of this gene belongs to the ligand-gated ionchannel receptor superfamily. This gene encodes subunit A of thetype 3 receptor for 5-hydroxytryptamine (serotonin), a biogenichormone that functions as a neurotransmitter, a hormone, and amitogen. This receptor causes fast, depolarizing responses inneurons after activation. It appears that the heteromericcombination of A and B subunits is necessary to provide the fullfunctional features of this receptor, since either subunit aloneresults in receptors with very low conductance and responseamplitude. Alternatively spliced transcript variants encodingdifferent isoforms have been identified.
Bio References: Gatt, J.M., et al. Biol. Psychiatry 68(9):818-824(2010)Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Gatt, J.M., et al. Depress Anxiety 27(8):752-759(2010)Ruano, G., et al. Pharmacogenomics 11(7):959-971(2010)Hammer, C., et al. Pharmacogenomics 11(7):943-950(2010)
Primary Accession: P46098