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CA7-H52A9-100ug CA7-H52A9-1mg

Human Cadherin-17 / CDH17 Protein, Mouse IgG1 Fc Tag

ACROBiosystems

DESCRIPTION

Human Cadherin-17 Protein, Mouse IgG1 Fc Tag (CA7-H52A9) is expressed from human 293 cells (HEK293). It contains AA Gln 23 - Met 787 (Accession # Q12864-1).

DETAILS

  • Tag: C-mFc(mIgG1)
  • Host: HEK293
  • Size: 1mg
  • Buffer: 20 mM Tris, 150 mM NaCl, pH8.0
  • Format: Powder
  • Purity: 90%
  • Storage: -20℃
  • Category: Other Recombinant Proteins
  • Molecule: Cadherin-17
  • Conjugate: Unconjugated
  • Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
  • Background: Cadherin-17, also known as liver-intestine (LI) Cadherin, belongs to the cadherin family of calcium-dependent cell adhesion molecules. In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach.
  • Exp Region: Gln 23 - Met 787
  • Characteristics: This protein carries a mouse IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 111.2 kDa. The protein migrates as 130-135 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
  • Endotoxin Level: 1.0 EU per μg
  • Molecular Weight: 111.2 kDa
  • Shipping Condition: RT
  • Species Reactivity: Human
  • Extra Shippinghandling Fee: Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/A48-Shipping-and-Payments.html