FUT3 Antibody (C-term) Blocking Peptide

DETAILS

Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Gene Id: 2525
Category: Peptides; Blocking Peptides
Subtitle: Synthetic peptide
Gene Name: FUT3
Other Names: Galactoside 3(4)-L-fucosyltransferase, Blood group Lewis alpha-4-fucosyltransferase, Lewis FT, Fucosyltransferase 3, Fucosyltransferase III, FucT-III, FUT3, FT3B, LE
Availability: 2 weeks
Bio Background: FUT3 comprises a set of fucosylated glycosphingolipids that are synthesized by exocrine epithelial cells and circulate in body fluids. The glycosphingolipids function in embryogenesis, tissue differentiation, tumor metastasis, inflammation, and bacterial adhesion. They are secondarily absorbed to red blood cells giving rise to their Lewis phenotype. This protein is a member of the fucosyltransferase family, which catalyzes the addition of fucose to precursor polysaccharides in the last step of Lewis antigen biosynthesis. It encodes an enzyme with alpha(1,3)-fucosyltransferase and alpha(1,4)-fucosyltransferase activities.
Bio References: Park, H.D., et al. Korean J Lab Med 30(1):51-57(2010)Matzhold, E.M., et al. Transfusion 49(10):2097-2108(2009)Norden, R., et al. Glycobiology 19(7):776-788(2009)Liu, J., et al. J. Exp. Clin. Cancer Res. 28, 154 (2009) Isla Larrain, M., et al. J. Exp. Clin. Cancer Res. 28, 121 (2009) Holmes, E.H., et al. J. Biol. Chem. 275(32):24237-24245(2000)
Primary Accession: P21217