HADHB Antibody (C-term) Blocking Peptide

DETAILS

Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Gene Id: 3032
Category: Peptides; Blocking Peptides
Subtitle: Synthetic peptide
Gene Name: HADHB
Other Names: Trifunctional enzyme subunit beta, mitochondrial, TP-beta, 3-ketoacyl-CoA thiolase, Acetyl-CoA acyltransferase, Beta-ketothiolase, HADHB
Availability: 2 weeks
Bio Background: HADHB encodes the beta subunit of the mitochondrial trifunctional protein, which catalyzes the last three steps of mitochondrial beta-oxidation of long chain fatty acids. The mitochondrial membrane-bound heterocomplex is composed of four alpha and four beta subunits, with the beta subunit catalyzing the 3-ketoacyl-CoA thiolase activity. Mutations in this gene result in trifunctional protein deficiency. The encoded protein can also bind RNA and decreases the stability of some mRNAs. The genes of the alpha and beta subunits of the mitochondrial trifunctional protein are located adjacent to each other in the human genome in a head-to-head orientation.
Bio References: Purevsuren, J., et al. Mol. Genet. Metab. 98(4):372-377(2009)Bogenhagen, D.F., et al. J. Biol. Chem. 283(6):3665-3675(2008)Wang, R., et al. Zhonghua Fu Chan Ke Za Zhi 41(10):672-675(2006)Hillier, L.W., et al. Nature 434(7034):724-731(2005)
Primary Accession: P55084