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SI0-H52H9-100ug SI0-H52H9-1mg

Human Siglec-10 Protein, His Tag (MALS verified)

ACROBiosystems

DESCRIPTION

Human Siglec-10, His Tag (SI0-H52H9) is expressed from human 293 cells (HEK293). It contains AA Met 17 - Thr 546 (Accession # Q96LC7-1).

DETAILS

  • Tag: C-10×His
  • Host: HEK293
  • Size: 100ug
  • Buffer: 25 mM MES, 150 mM NaCl, Arginine, pH5.5
  • Format: Powder
  • Purity: 95%
  • Storage: -20℃
  • Category: Bio-Markers & CD Antigens
  • Molecule: Siglec-10
  • Accession: NP_149121.2
  • Conjugate: Unconjugated
  • Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
  • Background: The siglecs (sialic acid-binding Ig-like lectins) are a distinct subset of the Ig superfamily with adhesion-molecule-like structure. We describe here a novel member of the siglec protein family that shares a similar structure including five Ig-like domains, a transmembrane domain, and a cytoplasmic tail containing two ITIM-signaling motifs. Siglec-10 was identified through database mining of an asthmatic eosinophil EST library. The Siglec-10-VAP-1 interaction seems to mediate lymphocyte adhesion to endothelium and has the potential to modify the inflammatory microenvironment via the enzymatic end products.
  • Exp Region: Met 17 - Thr 546
  • Swiss-prot: Q96LC7-1
  • Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 60.1 kDa. The protein migrates as 65-80 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
  • Endotoxin Level: 1.0 EU per μg
  • Molecular Weight: 60.1 kDa
  • Shipping Condition: RT
  • Species Reactivity: Human
  • Extra Shippinghandling Fee: Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/A48-Shipping-and-Payments.html