BODIPY-aminoacetaldehyde diethyl acetal

DESCRIPTION

A stable precursor to the fluorescent ALDH substrate BAAA; converted under acidic conditions to BAAA, which is cell-permeant and is converted intracellularly to BAA, which can be used to identify cells with high ALDH activity; co-application of BAAA with a P-gp inhibitor inhibits efflux of BAA; has been used to isolate human hematopoietic progenitor cells and via flow cytometry to sort cancer stem cells that contain high levels of ALDH; can be excited at 488 nm and displays and emission maximum of 512 nm

DETAILS

Inchi: InChI=1S/C20H28BF2N3O3/c1-5-28-20(29-6-2)13-24-19(27)10-9-16-7-8-17-12-18-14(3)11-15(4)25(18)21(22,23)26(16)17/h7-8,11-12,20H,5-6,9-10,13H2,1-4H3,(H,24,27)
Purity: ≥95%
Raptas: Application|Flow Cytometry||Application|Fluorescence||Product Type|Biochemicals|Labeling & Detection|Enzyme Substrates||Product Type|Biochemicals|Labeling & Detection|Fluorescent Probes||Research Area|Cancer|Cancer Stem Cell Research||Research Area|Cell Biology|Stem Cell Research
Smiles: [F][B-]1([N]2C(C=C(C(C)=C3)[N+]1=C3C)=CC=C2CCC(NCC(OCC)OCC)=O)[F]
Inchikey: LHPURSCMUYRRRM-UHFFFAOYSA-N
Cas Number: 247069-93-8
Formulation: A solution in methyl acetate
Storage Temp: -20
Shipping Temp: -20
Formula Markup: C20H28BF2N3O3
Formula Weight: 407.3
Shelf Life Days: 730