RAD23B Antibody (N-term) Blocking Peptide

DETAILS

Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Gene Id: 5887
Category: Peptides; Blocking Peptides
Subtitle: Synthetic peptide
Gene Name: RAD23B
Other Names: UV excision repair protein RAD23 homolog B, HR23B, hHR23B, XP-C repair-complementing complex 58 kDa protein, p58, RAD23B
Availability: 2 weeks
Bio Background: The protein encoded by this gene is one of two humanhomologs of Saccharomyces cerevisiae Rad23, a protein involved inthe nucleotide excision repair (NER). This protein was found to bea component of the protein complex that specifically complementsthe NER defect of xeroderma pigmentosum group C (XP-c) cellextracts in vitro. This protein was also shown to interact with,and elevate the nucleotide excision activity of 3-methyladenine-DNAglycosylase (MPG), which suggested a role in DNA damage recognitionin base excision repair. This protein contains an N-terminalubiquitin-like domain, which was reported to interact with 26Sproteasome, and thus this protein may be involved in the ubiquitinmediated proteolytic pathway in cells.
Bio References: Briggs, F.B., et al. Am. J. Epidemiol. 172(2):217-224(2010)Guillem, V.M., et al. Am. J. Hematol. 85(7):482-486(2010)Liu, C.Y., et al. Carcinogenesis 31(7):1259-1263(2010)Monsees, G.M., et al. Breast Cancer Res. Treat. (2010) In press :Rajaraman, P., et al. Neuro-oncology 12(1):37-48(2010)
Primary Accession: P54727