Biotinylated Cynomolgus CD79B Protein, His,Avitag™

DESCRIPTION

B-cell antigen receptor complex-associated protein beta chain (CD79b) is also known as B-cell-specific glycoprotein B29, Ig-beta,Immunoglobulin-associated B29 protein, B29 and IGB, which is a single-pass type I membrane protein containing one Ig-like V-type ( immunoglobulin-like ) domain and one ITAM domain.CD79b is required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR).CD79b can enhance phosphorylation of CD79A, possibly by recruiting kinases which phosphorylate CD79A or by recruiting proteins which bind to CD79A and protect it from dephosphorylation. Defects in CD79b are the cause of agammaglobulinemia type 6 (AGM6) that is a primary immunodeficiency characterized by profoundly low or absent serum antibodies and low or absent circulating B cells due to an early block of B-cell development.

DETAILS

Tag: C-10×His & C-Avi
Host: HEK293
Size: 25ug
Buffer: PBS, 0.2 M Arginine, pH7.4
Format: Powder
Purity: 90%
Source: Biotinylated Cynomolgus CD79B, His,Avitag (CDB-C82E5) is expressed from human 293 cells (HEK293). It contains AA Ala 30 - Asp 161 (Accession # NP_001248454.1).
Storage: -20℃
Category: MABSol® Biotin Labeled Proteins
Molecule: CD79B
Conjugate: Biotin-labeled
Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Exp Region: Ala 30 - Asp 161
Swiss-prot: A0A2K5WTH8-1
Package Size: 25ug*1
Characteristics: This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 18.9 kDa. The protein migrates as 30-35 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level: 1.0 EU per μg
Molecular Weight: 18.9 kDa
Shipping Condition: RT
Species Reactivity: Cynomolgus
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