ILA-H5256-100ug ILA-H5256-1mg
Human IL-31 RA Protein, Fc Tag
ACROBiosystems
DESCRIPTION
Interleukin-31 receptor subunit alpha is a protein that in humans is encoded by the IL31RA gene, also known as IL-31 receptor subunit alpha, IL-31RA, GLM-R, Gp130-like receptor, CRL3, GPL. Oncostatin M receptor (OSMR) and IL31RA form the heterodimeric receptor through which IL31 signals. IL31RA is a strong activator of STAT3 and STAT5, whereas STAT1 is only marginally tyrosine-phosphorylated. dditionally, demonstrate Jak1 binding to GPL and its activation in heteromeric complexes with the OSMRbeta but also in a homomeric receptor complex.
DETAILS
- Tag: C-Fc
- Host: HEK293
- Size: 100ug
- Buffer: Tris with Glycine, Arginine and NaCl, pH7.5
- Format: Powder
- Purity: 95%
- Source: Human IL-31 RA, Fc Tag (ILA-H5256) is expressed from human 293 cells (HEK293). It contains AA Ala 20 - Glu 519 (Accession # Q8NI17-1).
- Storage: -20℃
- Category: Bio-Markers & CD Antigens
- Molecule: IL-31 RA
- Accession: XP_011541444.1
- Conjugate: Unconjugated
- Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
- Exp Region: Ala 20 - Glu 519
- Swiss-prot: Q8NI17-1
- Package Size: 100ug*1
- Characteristics: This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 83.5 kDa. The protein migrates as 105-115 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Endotoxin Level: 1.0 EU per μg
- Molecular Weight: 83.5 kDa
- Shipping Condition: RT
- Species Reactivity: Human
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